This is a great build! Lots of fun!
I tried a variation on it - a ninja type. With no armor and lots of carrying capacity, I started developing not only the unarmed combat but also the throwing skill right from the start. There's lots of room in the inventory for knives and such.
I'm currently at level 19, and I've gone everywhere except Fathamurk, Picaroon, and Amireth. I used the rogue as the character base, and here's my stats:
Str - 47
Dex - 25
End - 30
Speed - 27
Int - 10
Wis - 10
Per - 15
Con - 15
Unarmed combat: 36
Thrown weapons: 12
Medicine: 9 (helps hit point regen)
Hide in Shadows: 12
Move silently: 8
Pick locks: 10
I've also got points in Lore, Cartography, Spot Hidden, and Repair.
To Hit: 26 (normal combat mode)
Max Damage (normal combat mode): 32+2 (thanks to Viscerator amulet)
In power combat mode, max damage is 42+2. My problem early on was remembering to switch to power mode before using the feat.
I like the Viscerator amulet rather than Animal Range because it adds 5 to speed, which also increases damage.
One thing I noticed with the Unarmed combat skill is that additional points in UA beyond 32 increases the To Hit and Max Damage stats, so even though you still only get the 4X damage feat every 4-5 rounds, combat skills do improve.
Many enemies do die with a single blow, depending on the random generation for the amount of damage your hit does. Those that don't will die with one or two extra punches. I like to soften up an enemy with a volley of knives before they reach me, and then deliver the fatal blow by hand.
There are some enemies that are much tougher, like the Dwarves and Taurax, but fortunately I can usually hit them, then back away for a few rounds until the feat recharges, hit them again, and repeat until they go down. The Hide in Shadows skill really helps with that.
Defending against ranged attacks was fairly simple once I developed the Hide in Shadows skill. I just carried lots of Predator Sight and Cats Eyes potions with me into dark dungeons and used the dark to reduce enemies' to-hit.
Defending against many multiple enemies is challenging, as you say, but the ranged attacks with throwing weapons helps with that. Plus I rely on the Hide in Shadows skill, Invisibility potions, and Haste potions.
I do find I have tons more coin to spend, so I keep an ample supply of useful potions in my inventory. And if I don't find any knives in the dungeons, I'll buy them from vendors. But I'm sure I'll have tons of unspent treasure before this build is done - much more than other builds!
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